Scientist

Job Title: Scientist
Location: Malvern, PA
Duration: 2 years+
 
Job Summary:
The Advanced Therapies, Functional Potency Method Development group is seeking an energetic, highly motivated scientist to support CAR-T cell therapies. The contactor will serve as a specialist in binding assay method development and assay validation.
 
Responsibilities:

• Plan and execute ELISA, AlphaLISA, luciferase reporter, and other plate-based assays
• Test samples across all CAR-T cell therapy programs
• Maintain healthy cultures of immortalized cell lines according to requirements
• Help keep a large inventory of reagent stocks maintained and well organized
• Maintain good electronic lab notebook (ELN) practices to ensure proper data documentation
• Demonstrate excellent communication and interpersonal skills
• The candidate is expected to work effectively in a team environment and well as contributing individually to meet project objectives and timelines.
• Other duties to be assigned as necessary.

 
Qualifications:

• Master's degree with at least 1+ years of experience or Bachelor's degree with at least 3+ years of experience.
• Must have experience in an appropriate scientific discipline (cell biology, immunology, biological science, or related field).
• Prior experience running plate-based methods (e.g. ELISA, AlphaLISA, MSD, and luciferase reporter assays) is required.
• Prior experience with immortalized cell culture (adherent and suspension cells) is required.
• Must have prior experience with cell counting
• Must have strong analytical problem solving, planning and organizational skills

 
Preferred Skills:

• Hands-on experience with CAR-T or other cell and gene therapy products
• Experience with co-culture functional assays in immuno-oncology
• Experience in analytical method development
• Experience in analytical method qualification and validation
• Experience with Kinexa and Biacore
• Experience with MSD
• Knowledge of ICH (Q2) R2 standards

 
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