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Job Requirements of Scientist III:
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Employment Type:
Contractor
-
Location:
Cambridge, MA (Onsite)
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Scientist III
Careers Integrated Resources Inc
Cambridge, MA (Onsite)
Contractor
Title: Scientist III
Location: Cambridge, MA
Duration: 18 Months+ Possible Extension
Pay Range: $85-$90/hr. on w2
Manager Notes:
Location: Cambridge, MA
Duration: 18 Months+ Possible Extension
Pay Range: $85-$90/hr. on w2
Manager Notes:
- 100% onsite, 6 months with potential for extension
- PhD (Immunology, Neuroscience, Cell Biology, or related). Strong background in neuroimmunology or immune cell biology (CNS, neuroinflammation, or ophthalmology).
- Lab-based role focused on neuroimmunology and retinal disease research Design and execution of experiments to support target validation and preclinical programs.
- Hands-on experience with assay development + optimization (ELISA, MSD required)
- Experience with primary immune cells (isolation, activation, functional assays)
- Strong cell culture experience (adherent lines + iPSC-derived cells preferred)
- We are seeking a motivated and skilled Scientist to join our Retinal Immunology and Neuroinflammation team as a contingent worker. The successful candidate will contribute to cutting-edge research aimed at understanding immune mechanisms in retinal diseases, supporting our mission to develop transformative therapies for patients.
- PhD in Immunology, Neuroscience, Cell Biology, or a related field with 0–3 years of postdoctoral or industry experience OR Bachelor's or Master's degree in a relevant scientific discipline with 4–7 years of hands-on laboratory research experience
- Demonstrated experience in neuroimmunology, including knowledge of immune cell biology in neurological or ophthalmic diseases
- Proven expertise in assay development and troubleshooting, with the ability to independently design, optimize, and validate experimental protocols
- Proficiency in ELISA/MSD for quantitative protein detection and multiplex analysis
- Experience with cell culture, including maintenance and passaging of adherent cell lines as well as iPSC-derived cell types
- Experience working with primary immune cells (e.g., isolation, activation, and functional characterization)
- Ability to work independently in a laboratory setting, managing experiments with minimal supervision while maintaining rigorous scientific standards
- Strong cross-functional collaboration skills, with the ability to work effectively across teams
- Experience with co-culture systems or advanced in vitro models (e.g., organoids, 3D cultures, organ-on-a-chip)
- Experience with live-cell and high-content imaging and analyses
- Background or research experience in retinal disease
- Design and execute experiments to investigate and translate immune and neuroinflammatory mechanisms into therapeutic disease programs, supporting target validation from discovery through preclinical development
- Collaborate cross-functionally with internal teams and external partners to support the screening of preclinical candidates across diverse modalities, using target- and disease-relevant functional readouts to drive program decisions
- Develop, optimize, and validate immunological and cell-based assays in support of research programs
- Maintain accurate and detailed laboratory records in compliance with internal documentation standards
- Analyze, interpret, and present experimental data to internal stakeholders
- Contribute to scientific discussions and help drive innovation within the team
- Strong analytical and problem-solving skills
- Excellent written and verbal communication
- Detail-oriented with a commitment to data integrity and reproducibility
- Adaptable and proactive in a fast-paced research environment
- Collaborative mindset with a patient-focused approach to science
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