Scientist - Analytical Development

Job Title: Scientist - Analytical Development
Location: Cambridge, MA 02142
Duration: 9 months+

Pay Rate: $50/hr. on w2
 
Top skills: Chromatographic separation mechanisms in both gas phase and liquid phase and structure elucidation expertise and MS
 
Job Summary:
The Scientist, is part of Analytical Development Starting Material Group and will be responsible for

• Develop, qualify and transfer GC, HPLC, UPLC and mass spectrometry-based assays of starting materials, raw materials, intermediates, and excipients to suppliers, CMOs and QC.
• Identify impurity profiles and provide data to set impurity limits.
• Understand and apply advanced scientific principles, theories, concepts, practices, and standards to process and analytical development.
• Author and review method development and qualification reports and SOPs for test methods, as well as transfer / qualification protocols and reports related to critical starting materials / intermediates / excipients.
• Provide analytical support externally and internally.

 
Qualifications:

• Ph.D. in Analytical Chemistry, Organic Chemistry or related disciplines with > 1 year biopharmaceutical experience or equivalent.
• Master’s degree with > 5 years biopharmaceutical experience respectively, with demonstrated chromatographic separation, method development / qualification and structure elucidation expertise.
• Strong knowledge of fundamental chromatographic separation mechanisms in both gas phase and liquid phase, proven years of excellent hands-on method development and optimization experience on HPLC, UPLC and GC for separation of molecules and isomers.
• Sound background in organic chemistry with a focus on structure characterization and elucidation of synthetic molecules through determination and interpretation of mass spectrometry and NMR data.
• Self-motivated, excellent communication, writing and reviewing skills.
• Familiarity with Waters and Agilent (U)HPLC and Mass Spectrometery hardware.
• Familiarity with Empower, Masslynx, Masshunter, and XCalibur CDS are preferred
• Comment Must have either PHD with 1 year of exp or Masters with 5 years of exp.