Scientist II

Job Title: Scientist II
Location: Boston, MA
Duration: 06 Months+

Pay range: $42 - $44/hr. on W2
 
Job Description:
Contractor – Protein Analytics
Client. is a global health care leader with a diversified portfolio of prescription medicines, vaccines, and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Client has codified its legacy for over a century. Client success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
Early Biologics Characterization – Boston of Client Research Laboratories (MRL) is seeking a contractor to execute on existing protein analytics workflows. Specifically, to perform intact MS, pepProduct mapping and other biophysical assays such as SEC, HIC, CE-SDS, DSF, DLS, Buffer Exchange.
 

• In this role you will build and then use a combination of skills to help with the biological characterization workflow.
• Additional laboratory automation skills are desired but not required.
• This role will require an eagerness to learn and an ability to work with different teams and different equipment to operate a robust characterization platform.
• Your efforts will be a complement and core resource to existing capabilities and will serve to expand the team’s ability to interrogate biologics diversity to identify optimal leads.
• You will have the opportunity to apply your enthusiasm and technical skills as a member of Discovery Biologics - Boston to support and help drive multidisciplinary biotherapeutic discovery programs.

 
Responsibilities:

• Operate and maintain existing mass spectrometry platforms and implement new workflows for protein characterization
• Perform LC-MS data analysis using various software and bioinformatic tools to elucidate the quality attributes of therapeutic proteins and other Client modalities.
• Troubleshoot automation methods and devices to maintain optimal high throughput protein analyses
• Generate frequent characterization summary reports.
• Follow and improve Standard Operating Procedures for biologics characterization workflows.

 
Qualifications:

• A minimum of a B.S in a relevant field (e.g. protein sciences, chemical or bioengineering, biochemistry or similar) with additional training being desirable.

 
Experience:

• BS with 6+ years of experience/MS with 4+years./PHD with 1-3years.
• Industry experience is preferred.

 
Required experience and skills:

• Experience with mass spectrometry and other biophysical assays workflows and their inherent data management.
• Knowledge and hands on experience in LC-MS based sample preparation for proteins
• Strong problem solving and communication skills.
• Ability to multitask, time management, and prioritize activities.

 
Preferred experience and skills:

• Experience with operating high resolution MS instruments such as Agilent Q-TOF, Thermo Orbitraps (e.g. QE+, QE-HF, Exploris 480) and liquid handling platforms such as Vanquish, Acquity UPLC.
• Experience analyzing data with BioPharma finder, BioConfirm and other MS software is a plus
• Experience with EMPOWER is a plus
• ELN knowledge is desirable

 
Note:

• 100% onsite role.

 
 
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