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Computational Scientist - Oncology

Careers Integrated Resources Inc Mississauga, Ontario (Onsite) Contractor
Job Title: Computational Scientist – Oncology
Location: Mississauga, ON (Hybrid)
Duration: 12 Months
Shift: Standard business hours (Hybrid work arrangement)

Role Overview
The Oncology team within the Computational Biology and Translation Pillar at Client's Global Computational Sciences (gCS) is seeking a highly motivated Computational Scientist (Contract). This role focuses on applying advanced computational and statistical methods to analyze preclinical and clinical datasets, with a strong emphasis on Breast Cancer. The scientist will contribute to drug discovery and translational research by interpreting multi-omics data to generate meaningful insights into disease mechanisms and treatment responses.

Key Responsibilities
  • Conduct in-depth analysis of bulk RNA-seq, ATAC-seq, WES, and single-cell datasets.
  • Develop and implement statistical models and machine learning approaches to analyze and integrate complex biological data.
  • Translate analytical findings into actionable biological insights related to disease biology and drug mechanisms.
  • Present results to internal stakeholders and respond to scientific queries.
  • Document code, workflows, and findings to support reproducibility and standardization.
  • Collaborate across multidisciplinary teams to support ongoing oncology research initiatives.

Qualifications & Skills
  • Ph.D. in Computational Biology, Bioinformatics, Systems Biology, or a related field (postdoctoral experience is a plus).
  • Proven publication record in computational or cancer biology.
  • Minimum 6 years of experience analyzing large-scale omics datasets (e.g., RNA-seq, WES).
  • Expertise in:
    • Multivariate statistical analysis
    • Drug response and perturbational data analysis
    • Multimodal data integration
    • Predictive and prognostic modeling
  • Deep understanding of cancer biology, especially Breast Cancer.
  • Strong programming skills in R, Python, and shell scripting.
  • Experience using Git and working with high-performance computing (HPC) systems.
  • Demonstrated ability to work independently and meet deadlines with minimal supervision.
  • Excellent communication skills and a collaborative mindset.
  • Strong curiosity and drive to learn in the fields of oncology and computational biology.
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Job Snapshot

Employee Type

Contractor

Location

Mississauga, Ontario (Onsite)

Job Type

Other

Experience

Not Specified

Date Posted

05/09/2025

Job ID

25-45883

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