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Job Requirements of DMPK Project Representative:
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Employment Type:
Contractor
-
Location:
Lexington, MA (Onsite)
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DMPK Project Representative
Careers Integrated Resources Inc
Lexington, MA (Onsite)
Contractor
Job Title: DMPK Project Representative
Job Location: Lexington, MA
Job Duration: 12 Months (possibility of extension)
Payrate:$125 - 142/hr. on w2
TOP SKILLS PER MGR:
PURPOSE:
ESSENTIAL FUNCTIONS:
QUALIFICATIONS:
Job Location: Lexington, MA
Job Duration: 12 Months (possibility of extension)
Payrate:$125 - 142/hr. on w2
TOP SKILLS PER MGR:
- Project facing role (3+ years)
- ADME or PKPD subject matter expert
- Someone with relevant publications/abstracts that speak to metabolism/drug interaction/PKPD modeling.
PURPOSE:
- The Sr. Scientist will act as a DMPK project representative and provide scientific leadership in the discovery of small molecule drug candidates by integrating DMPK strategy to progress drug discovery projects across several therapeutic areas.
- This will be achieved by proposing and leading internal and external research efforts to support project goals.
- The Sr. Scientist will work closely with pharmacology and medicinal chemistry team, lead DMPK efforts to optimize molecules across a variety of therapeutic areas utilizing in vitro, in vivo, and in silico methods and models to generate novel chemical matter with drug-like properties.
- The Sr. scientist will collaborate with outsourcing managers to identify and manage CROs with specialized ADME capabilities, and build and maintain relationships ADME experts to leverage expertise and harmonize ADME strategy.
- The individual will be seen across the company and beginning to be viewed externally as a method/subject expert within small molecule DMPK.
- Reports to the head of the relevant DMPK department
- Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at client; & frequent interaction with project managers & other colleagues across global R&D. Individual may direct the work of other staff members.
- Individual will interact with external research collaborators both academia- & industry-based.
ESSENTIAL FUNCTIONS:
- Function as DMPK project representative for global, cross-functional small molecule project teams to achieve project goals
- Provide expert-level guidance to experimental plans and data interpretation with a strong expertise in either ADME/PK/DDI or PK/PD modeling and simulation
- Troubleshoot highly complex tasks through independent and team-based efforts
- Demonstrate deep subject matter expertise and in-depth experience, as well as creative, independent thinking and solutions for addressing critical scientific questions
- Make independent decisions related to day-to-day experimental activities
- Work closely with CROs to assume responsibility for DMPK experimental design, implementation, and interpretation
- Analyze complex data with high degree of sophistication, connect disparate datasets to reach conclusions, and communicate project updates and experimental results to relevant stakeholders
- Ensure proper documentation of all experiments and data
- Collaborative teamwork
- Communicate regularly with international colleagues.
- Actively participate in cross-functional teams and meetings to drive project success
- Achieve business goals, share learnings, knowledge and skills & promote cross-functional teamwork
- Share knowledge & expertise to expand team capabilities and goals
- Demonstrate superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization
- Write and review collaborative research manuscripts, project documents, and milestone documents
- Complete assignments requiring expert-level knowledge of techniques and practices related to the research area
- Represent the organization as client-subject matter expert by attending and presenting at scientific conferences and global meetings
QUALIFICATIONS:
- Bachelor 's Degree within subject matter expertise required.
- 18+ years’ relevant experience required, or a master’s degree with 12+ years’ relevant experience, or a Doctoral degree in with 6+ years’ post-doctoral and/or industry relevant experience can be considered.
- Relevant required experience includes: Excellent understanding of ADME principals with knowledge of PK/PD modeling or biotransformation highly desirable
- Preferred experience includes: Prior experience working in a fully or hybrid ADME-outsourced models
- Demonstrates excellent verbal and written communication skills.
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