System Engineer III

Job Title: System Engineer III
Location: Waltham, MA ( Hybrid working model with a minimum of three days per week on site in Waltham, MA.)
Duration: 12 Months+ Possible Extension

Pay Range: $90 - $96/hr. on W2
 
Manager Notes:
MUST HAVE SKILLS:

• Education : Bachelor’s degree or higher in Computer Science, Software Engineering, Data Science, or a related field.
• MS and PHD accepted / Over 5 years of exp accepted.
• Strong experience working in agile environments with a customer oriented mindset.
• Proven experience deploying and operating applications in production.
• Python programming skills. GitHub Actions and CI/CD pipeline implementation.
• Kubernetes based container orchestration.
• GitOps practices (ArgClient or equivalent). Dev Ops, automation.
• Production deployment of machine learning models and MLOps practices.
• API and/or web application development.
• Production deployment of machine learning models and MLOps practices.
• Familiarity with major cloud platforms (AWS, Azure, or GCP).

 
Preferred qualifications/ nice to Have Skills:

• Experience in pharmaceutical, biotechnology, or life sciences environments.
• Awareness of drug discovery, vaccine development, or experimental sciences.
• Experience with workflow orchestration tools such as Metaflow. Some knowledge in orchestration frameworks, preferred in Metaflow, frameworks, operation.
• AI assisted software engineering experience.
• Agents skills dedicated format, write small passages for skills.
• Contributions to open source or technical communities.
• Experience designing scalable data engineering solutions.

 
ABOUT THE MRNA CENTER OF EXCELLENCE:

• Client’s mRNA Center of Excellence (CoE) represents an annual investment of approximately €400 million to accelerate the development of nextgeneration vaccines.
• With around 400 dedicated employees across Cambridge, Massachusetts (USA) and Marcyl’Etoile, France, the CoE integrates endtoend mRNA vaccine capabilities across Research & Development, Digital, and CMC functions.
• Beyond pandemic preparedness, the CoE drives innovation in mRNA technologies with a strong focus on thermostability, tolerability, and routine vaccination use cases.
• Advanced AI and machinelearning approaches—such as lipid nanoparticle prediction and mRNA sequence optimization—are embedded in the research strategy to accelerate scientific decisionmaking and development timelines.

 
MISSION STATEMENT:

• The Senior Systems Engineer – Production AI will join the mRNA Systems Engineering team to design, build, and operate productiongrade systems based on AI and machinelearning and that accelerate mRNA vaccine research and development.
• Working in a highly agile, crossfunctional environment at the interface of software engineering, AI/ML, and pharmaceutical sciences, the role contributes to build scalable digital products that bring predictive models into production and empower scientific users across Vaccines R&D.

 
KEY RESPONSIBILITIES:

• Design, develop, deploy, and operate productiongrade AI/ML systems and data pipelines in an agile environment.
• Build, maintain, and optimize CI/CD pipelines using GitHub Actions to enable automated testing and deployment.
• Deploy and operate applications on Kubernetes using GitOps practices (e.g., ArgClient).
• Develop userfacing applications through APIs and/or graphical interfaces.
• Deploy predictive models into production environments with a strong focus on reliability, scalability, and observability.
• Build and optimize compute pipelines supporting data processing and model training.
• Collaborate closely with data scientists, computational biologists, and vaccine researchers to translate scientific needs into robust digital solutions.
• Actively participate in agile ceremonies and contribute to continuous improvement of team practices.
• Ensure high standards for code quality, documentation, and knowledge transfer.
• Communicate complex technical concepts clearly to both technical and nontechnical stakeholders.

 
REQUIRED QUALIFICATIONS:
Education:

• Bachelor’s degree or higher in Computer Science, Software Engineering, Data Science, or a related field. Advanced degrees are valued but not required.

Experience:

• Minimum of 5 years of professional software engineering experience.
• Demonstrated delivery of productionlevel systems with measurable impact.
• Strong experience working in agile environments with a customeroriented mindset.
• Proven experience deploying and operating applications in production.

Technical Skills:

• GitHub Actions and CI/CD pipeline implementation.
• Kubernetesbased container orchestration.
• GitOps practices (ArgClient or equivalent).
• Strong Python programming skills.
• API and/or web application development.
• Production deployment of machinelearning models and MLOps practices.
• Familiarity with major cloud platforms (AWS, Azure, or GCP).

Language:

• English: fluent (mandatory). French: nice to have.

 
PREFERRED QUALIFICATIONS:

• Experience in pharmaceutical, biotechnology, or lifesciences environments.
• Awareness of drug discovery, vaccine development, or experimental sciences.
• Experience with workflow orchestration tools such as Metaflow.
• Experience in mentoring or technical training.
• Contributions to opensource or technical communities.
• Experience designing scalable data engineering solutions.

 
WHAT WE’RE LOOKING FOR:

• Client values demonstrated impact, collaboration, and scientific curiosity.
• For the right candidate, depth of expertise and delivery track record are more important than the number of years of experience.
• The ideal candidate is a strong collaborator, comfortable working with scientific users, and motivated to build impactful digital products that advance mRNA vaccine development.

 
WHY JOIN Client VACCINES R&D:

• Contribute at the forefront of mRNA vaccine innovation and AIenabled pharmaceutical R&D.
• Collaborate with worldclass scientists and engineers in a purposedriven organization.
• Make a direct impact on global public health.
• Live Client’s values: Aim Higher, Act for Patients, Be Product, and Lead Together.
• Access stateoftheart R&D facilities and digital platforms.

 
WORK ENVIRONMENT:

• Hybrid working model with a minimum of three days per week on site in Waltham, MA.
• Agile and fastpaced team environment focused on rapid iteration and delivery.
• Strong crossfunctional collaboration across Vaccines R&D, Digital, and CMC.