Scientist - III (Senior)

The Department of Neuroscience is seeking a bioanalytical scientist to join the MRL Discovery organization in West Point, PA.

In this position, you will be responsible for developing mass spectrometry-based assays for use in preclinical drug development with a focus on neurodegenerative diseases with high unmet medical needs.

Appointees will work within multidisciplinary teams focused on the discovery of Client drug targets and development of biomarkers for clinical translation supporting new therapeutics.

Applicants should have expertise in development of quantitative mass spectrometry assays to support follow-on validation of discovery data for biomarker development.

If you are driven and open to learning in a team environment, come join our team.



Quals--

Job Title: Scientist III, Mass Spectrometry/Analyst, Discovery Neuroscience.



Education requirements

PhD with industry or academic experience or Master's with at least 2-3 years of industry experience.



Experience/skills required:

Hands-on experience in the development and technical validation of quantitative LC-MS/MS assays using MRM/PRM acquisition

Experience in data analyses covering relative to absolute quantification

Expertise in sample processing and prefractionation across cell, tissue and fluid specimens

Experienced in using automated liquid handling platforms

Experience working collaboratively within cross-functional teams

Self-motivated and resourceful with a demonstrated ability to generate robust and reproducible data in a timely manner

Well-developed oral and written communication skills



Desired Competencies (Preferred / not required):

Hands-on experience performing unbiased, quantitative discovery analyses with high resolution LC-MS instrumentation (i.e. DDA, DIA approaches using label-free or TMT quantification)

Proficiency in data processing with tools such as MetaboAnalyst, Skyline, MaxQuant, Proteome Discoverer, EncyclopeDIA or similar.

Mass spectrometry-based targeted quantitative lipid analyses or discovery lipidomics.



Note:

100% lab based role.



Key skills to focus:-

Hands on Mass spectrometry assays expertise needed.

Developing quantitative assays using Mass spectrometry.

Proficiency with tools such as MetaboAnalyst, Skyline, MaxQuant, Proteome Discoverer, EncyclopeDIA or similar.